While AOL has put together a rosy list of the "hottest on-set hookups," complete with lusty make-out pictures and lovey-dovey tales from between the sheets, we feel obligated to point out that not every "hot" and heavy on-set romance leads to a fairy tale ending. In fact, a few of these couples' choices to get busy in between scenes wreaked havoc on both their personal and professional lives, leading some to lose their spouses, their reps and, in Angelina Jolie's case, a tattoo or two. We put together our own list of the top five most ill-fated on-set hookups, mainly to remind these bed-hopping stars that sometimes it's best to just say no to illicit trailer sex.

5. Julia Roberts and Lyle Lovett: After only three weeks of courtship following their first meeting on the set of The Player, the crooner managed to tie the knot with the Pretty Woman. But all the flack Julia received for falling in the sack with such an odd-looking, unknown duck wasn't the least bit worth it; their 1993 wedding turned into a 1995 separation, leaving Jules looking just this side of desperate.

4. Jennifer Aniston and Vince Vaughn: Speaking of desperate, the weeklies' favorite pity princess was still grieving or whatever over the loss of Brad to Angelina, and her are-they-or-aren't-they "relationship" with Vince Vaughn on the set of The Breakup just made her look even more pity-worthy after Vaughn's repetitive, close-to-insulting denials to the press.

3. Angelina Jolie and Billy-Bob Thornton: Embarrassing enough as it is to get dumped by someone like Billy Bob, it was his alleged reasoning that made this breakup particularly gruesome. According to countless reports, Thornton just didn't feel like being a dad to Angie's little bundle of joy Maddox. However, the outcome (Chosen One! Brad Pitt!) was hardly anything to frown about.

2. Jennifer Lopez and Ben Affleck: Gigli. We're sorry, that's really all there is to say.

1. Meg Ryan and Russell Crowe: Talk about losing a rock solid reputation; America's sweetheart, married to a classic hunk (with a cute kid to boot!), ran off with the (then) Australian lothario while filming Proof Of Life in 2000. The results? Out with the marriage and the good girl cred, on with the racy movies and trout pout. Disaster.

• TOP 25 HOTTEST ON-SET HOOKUPS [AOL Movies]

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